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Page 1
Heart Failure Stimulates Tumor Growth by Circulating Factors.
Meijers WC, Maglione M, Bakker SJL, Oberhuber R, Kieneker LM, de Jong S, Haubner BJ, Nagengast WB, Lyon AR, van der Vegt B, van Veldhuisen DJ, Westenbrink BD, van der Meer P, Silljé HHW, de Boer RA. Meijers WC, et al. Circulation. 2018 Aug 14;138(7):678-691. doi: 10.1161/CIRCULATIONAHA.117.030816. Circulation. 2018. PMID: 29459363 Free article.
We identified several proteins (including serpinA3 and A1, fibronectin, ceruloplasmin, and paraoxonase 1) that were elevated in human patients with chronic HF (n=101) compared with healthy subjects (n=180; P<0.001). Functionally, serpinA3 resulted in marked proli …
We identified several proteins (including serpinA3 and A1, fibronectin, ceruloplasmin, and paraoxonase 1) that were elevated in human …
Increased SERPINA3 Level Is Associated with Ulcerative Colitis.
Zhang J, Wang W, Zhu S, Chen Y. Zhang J, et al. Diagnostics (Basel). 2021 Dec 16;11(12):2371. doi: 10.3390/diagnostics11122371. Diagnostics (Basel). 2021. PMID: 34943607 Free PMC article.
The PubMed database was used to screen new genes that have not been reported, and SERPINA3 was selected. The correlation between SERPINA3 and other inflammatory factors was analysed by Spearman correlation analysis. ...ROC analysis indicated that SERPINA3 cou …
The PubMed database was used to screen new genes that have not been reported, and SERPINA3 was selected. The correlation between S …
LAMB3 Promotes Intestinal Inflammation Through SERPINA3 and Is Directly Transcriptionally Regulated by P65 in Inflammatory Bowel Disease.
Liu F, Xu W, Wang Y, Huang Z, Zhu Z, Ou W, Tang W, Fu J, Liu C, Gu Y, Liu Y, Du P. Liu F, et al. Inflamm Bowel Dis. 2024 Feb 1;30(2):257-272. doi: 10.1093/ibd/izad140. Inflamm Bowel Dis. 2024. PMID: 37454278
METHODS: LAMB3 expression was assessed in cultured intestinal epithelial cells, inflamed mucosal tissues of patients and mouse colitis models. ...Furthermore, RNA sequencing and replenishment experiments revealed that LAMB3 upregulated SERPINA3 to promote intesti …
METHODS: LAMB3 expression was assessed in cultured intestinal epithelial cells, inflamed mucosal tissues of patients and mouse coliti …
Plasma proteome signature of canine acute haemorrhagic diarrhoea syndrome (AHDS).
Huber L, Kuropka B, Doulidis PG, Baszler E, Martin L, Rosu A, Kulmer L, Frizzo Ramos C, Rodríguez-Rojas A, Burgener IA. Huber L, et al. PLoS One. 2024 Feb 8;19(2):e0297924. doi: 10.1371/journal.pone.0297924. eCollection 2024. PLoS One. 2024. PMID: 38330002 Free PMC article.
Acute haemorrhagic diarrhoea is a common complaint in dogs. In addition to causes like intestinal parasites, dietary indiscretion, intestinal foreign bodies, canine parvovirus infection, or hypoadrenocorticism, acute haemorrhagic diarrhoea syndrome (AHDS) is an impo …
Acute haemorrhagic diarrhoea is a common complaint in dogs. In addition to causes like intestinal parasites, dietary indiscretion, …
Broad up-regulation of innate defense factors during acute cholera.
Flach CF, Qadri F, Bhuiyan TR, Alam NH, Jennische E, Lönnroth I, Holmgren J. Flach CF, et al. Infect Immun. 2007 May;75(5):2343-50. doi: 10.1128/IAI.01900-06. Epub 2007 Feb 16. Infect Immun. 2007. PMID: 17307946 Free PMC article.
The majority of the up-regulated genes characterized were found to have an established or possible role in the innate defense against infections; these genes included the LPLUNC1, LF, VCC1, TCN1, CD55, SERPINA3, MMP1, MMP3, IL1B, LCN2, SOCS3, GDF15, SLPI, CXCL13, and MUC1 …
The majority of the up-regulated genes characterized were found to have an established or possible role in the innate defense against infect …
Protein expression in the liver and blood serum in chickens in response to Salmonella Enteritidis infection.
Polansky O, Seidlerova Z, Faldynova M, Sisak F, Rychlik I. Polansky O, et al. Vet Immunol Immunopathol. 2018 Nov;205:10-16. doi: 10.1016/j.vetimm.2018.10.006. Epub 2018 Oct 21. Vet Immunol Immunopathol. 2018. PMID: 30458997
However, mechanisms of the immune response and defence beyond the intestinal tract are less well-described. In this study, we therefore determined changes in protein abundance in the liver and blood serum in response to S. ...No functional category was significantly activa …
However, mechanisms of the immune response and defence beyond the intestinal tract are less well-described. In this study, we therefo …